I use AfterShot Pro 3, so I won't have a COW.
I've used DxO Photolab and it's predecessor DxO Optics Pro since 2006. Nothing compares. rien n’est comparable.
I'm looking to upgrade my processing for high ISO low light images and I'm leaning toward DXO Photolab 7. I'll check out a few others but so far DXO seems to fit my insanity better.