Does anyone arbitrarily lose their default shortcut keys in 2017?

Been using CD since 1992, currently using ver 2017 and I'm ready to dump CorelDraw from my regular workflow for good. Why? Because I can't seem to solve the issue with my default shortcut keys suddenly disappearing. One moment I'm working away, the next second I can't use CTRL-U or maybe F4 or sometimes C,E,T,B etc.

This concern permanently stays with the file. I can open another document alongside and everything works. I can close the troubled file and sometimes the keys come back, but most often not.

I have been in regular contact with Corel support and attempted and currently use their temporary solutions almost daily. I am hoping someone has had similar issues and can perhaps inform me I am a complete dolt for overlooking something.

If you have had anything similar happen to you, or Corel, should you have a permanent fix for this, I would sincerely appreciate your assistance.

Thank you.