Lost my brush save mode

Earlier this morning, I went through the process of creating a brush using Save Artistic Media Stroke. I wasn't able to find it afterward, and I did something—I know not what—and now the option to save is grayed out.

I attempted to unset the Read-only bit for this folder under Windows, but it won't stick. Using version 2017 under Windows 10. Should I reinstall? Or is there something else I can do?

Thanks,
John