Help with Colour Management in X6

Hello all,

I'm in desperate need of some help with colour settings in CDX6. I've scoured the net but only seem to find contradictions and half answers, so am hoping for some expert help! I'm running Windows 7 with an Eizo monitor and Epson B-510DN 3 colour inkjet printer. Basically I'd like to know the correct settings for the Default Settings in Colour Management as well as the correct choices in Print Options / Colour. I feel like I'm drowning in options and combinations!

Many thanks in advance.