Disable "Edit Across Layers" and make it a global default setting?

Hello!

You need place this code in ThisMacroStorage of GlobalMacros.gms:

Private Sub GlobalMacroStorage_DocumentOpen(ByVal Doc As Document, ByVal FileName As String)
Application.ActiveDocument.EditAcrossLayers = False
End Sub

Private Sub GlobalMacroStorage_DocumentNew(ByVal Doc As Document, ByVal FromTemplate As Boolean, ByVal Template As String, ByVal IncludeGraphics As Boolean)
Application.ActiveDocument.EditAcrossLayers = False
End Sub

After placement You must  restart CorelDRAW

Greetings!