working with icc profiles in X4; how to change colorsettings?

I work as a graphics designer in the Netherlands.

When creating a full color ad for a newspaper I use the Ghent recommended icc profile ISONewspapers to convert RGB pictures to CMYK in Photoshop (works better for me than Paint). I then import them in CDR X4, add text etc. When the advertismentlayout is final I print the add to a Distiller profile (also by the Ghent group) called NewspaperAds 1v3 (delivering certified pdf files to media is mandatory in the Netherlands). However when I open the pdf the images seems to be converted back to standard CMYK. Apparently I need to change settings in CDR and Adobe Acrobat 8. But I havent got a clue how and where......

Anyone any suggestion?