150 page book

I am getting ready to start a book that will consist of 150, 2 sided, pages that will be perfect bound. I am looking for any advice that will help in creating the CDX7 document file work without, hopefully, crashing due to the number of pages. What is the maximum number of pages that can be created in 1 file? The page size will be 8.5 x 11 and as each physical page will have two sides the document will consist of 300 pages. All the images placed in the document will be either pdf or jpeg with a few exceptions. Let me know if any additional info is needed.