Can't Publish to PDF!!

I regularly design multi-page design drawings for sign manufacturing, and was operating normally in X3 on a Dell Dual Core up to yesterday, when suddenly app won't successfully publish to PDF. It just spins, or produces a file that has blank pages or some huge empty file that shows it to be over 150MB in size (normally my files are under 8 MB).
I tried a complete uninstall/reinstall of program twice now, but only to have same results.

Anybody ever experience this kind of malfunction?  Thanks in advance....