Working with larger & more complex files; shutting down!

Hi all,

   I guess we can call this part two of an earlier post I made regarding color management.  While I am no longer having the color issue; I am experiencing application errors and shut down when working with large files.  When I say large,  I mean those close to or over a meg; those in which there are complex layers or those in which the canvas is more than a foot by a foot. When this happens, the program closes; so far only one file has been completely lost; it was one I had worked on previously and my auto save is set for every ten minutes but when the forced shut down occured and I restarted the application, the original file was still there but entirely blank, not one line on the whole thing.  Thank goodness for the back-up copy.

  I have two error reports but because they are so long, I did not want to post them unless requested.

Any ideas?

Thanks much,

~Lee